Dental FAQsWhat is Platelet Rich Fibrin (PRF)?

Platelet Rich Fibrin (PRF) is a yellow gel-like mixture of fibrin, platelets, white blood cells, stem cells and bone growth factors. This natural material is fabricated entirely from the patient’s own blood.

New technologies allow us to harvest blood and then produce a sufficient quantity of PRF from only 10-30 cc of blood, which is drawn from the patient’s arm the same as is done for blood testing in a medical doctor’s office.

How is PRF created?
The PRF is created by spinning the harvested blood in a centrifuge for just under 15 minutes.

PRF permits the body to take advantage of the normal healing pathways at a greatly accelerated rate. During the healing process, the body rushes many cell types to the wound in order to initiate the healing process. Platelets are one of those cell types.

Platelets perform many functions, including formation of a blood clot and release of growth factors (GF) into the wound. These growth factors; platelet derived growth factors (PDGF), transforming growth factor beta (TGF), and insulin-like growth factor (ILGF), function to assist the body in repairing itself by stimulating stem cells to regenerate new tissue.

The more growth factors released and sequestered into the wound, the more stem cells are stimulated to produce new tissue. Thus, PRF permits the body to heal faster and more efficiently. 

What does PRF have to do with dentistry?

A lot! Learn more about the relationship with PRF and dentistry in this article.

Learn More

Really curious about PRF? Take a deeper look by reading Platelet-rich fibrin: Basics of biological actions and protocol modifications.